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The Importance of Personalized Treatment

Effectiveness of osteoarthritis (OA) treatments vary from person to person, and treatment plans for OA of the knee  usually involve a combination of approaches designed specifically to suit each individual.

Preventing further damage

For patients with very progressed knee OA, surgery may remain the only option, but early diagnosis and treatment can often help prevent or slow down further damage to the joints, and enable patients to remain more active and productive.1-6.


1. Stages of knee OA progression.

Healthy Knee

  • Cartilage covers bone ends
  • Synovial fluid

Mild Knee OA

  • Cartilage covers bone ends
  • Synovial fluid

Moderate Knee OA

  • Cartilage covers bone ends
  • Synovial fluid

Severe Knee OA

  • Cartilage covers bone ends
  • Synovial fluid
  • Synovial fluid
  • Synovial fluid
  • Synovial fluid

Treatment Options

Note that severity of OA is not only a function of its radiographic appearance.

Treatment Options

Healthy Knee


Mild OA


Moderate OA


Severe OA

Increased Activity/Weight Loss
Pain Medication

While Total Knee Replacements (TKR) are on the rise globally, imposing a further burden on health care systems, recent studies have shown bracing to be a costeffective therapy that can provide pain relief, reduce medication intake, delay surgical intervention, and improve quality of life.11–15.

Benefits of Bracing

The Unloader One® OA knee brace from Össur, indicated for treatment of mild to severe Knee OA, can help patients stay active without causing further joint damage.

For some patients, the Unloader One can mean surgery is no longer a necessity, as their mobility is increased and pain is reduced. For others, the brace is used as an interim measure, postponing the need for surgery until they feel both mentally and physically prepared for the procedure.

Recent clinical research by the Steadman Philippon Research Institute demonstrated that the Unloader One decreases pain, improves function and reduces the usage of pain medication.*

  1. Kirane Y. et al. Lower Extremity Review, Sept 2010.
  2. Katz N, Losina E. Burden of OA – Health Services and Economics. OARSI Primer 2010.
  3. Agency for Healthcare Research and Quality (AHRQ). AHRQ Pub. No. 02-0023, May 2002.
  4. Briggs KK. et al. J Knee Surg 2012; 25:417–422. 14. Kirkley A. et al. J Bone Joint Surg1999.
  5. Pollo FE. et al. Am J Sports Med 2002.